Hyperlink management system
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Help Index

1. About Hyperlink Management System
2. How to create hyperlinks using the system
3. All database search
4. ID converter system
5. Downloading ID tables
6. Web Service
7. Collected databases/IDs
8. Release history

1. About Hyperlink Management System

Hyperlink Management System is a system for automatically updating and maintaining hyperlinks among major public databases in the field of life science. Everyday, we create corresponding tables of data IDs that are used in major databases for genes and proteins, and provide a cgi-program that returns correct and up-to-date URLs of corresponding data in many databases. By using the CGI program on this server, users can easily create hyperlinks to major databases in their own databases and homepages. Furthermore, on this web site, we provide useful tools such as "All Database Search", "ID converter system", and "Downloading ID tables".
This System was developed at the Biological Information Research Center of the National Institute of Advanced Industrial Science and Technology (AIST) with the financial support from the JST (2006-2008). Since 2008, the system is developed at the Biomedicinal Information Research Center of AIST with a support from the Integrated Database Project of the Ministry of Economy, Trade and Industry of Japan (a portal for the project: MEDALS).

Creative Commons License
This work is licensed under a Creative Commons Attribution 2.1 Japan License.
Please cite the paper below if you utilize the systems provided on this web site.
Imanishi T and Nakaoka H (2009) Hyperlink Management System and ID Converter System: enabling maintenance-free hyperlinks among major biological databases. Nucleic Acids Research 37(Web Server Issue) doi:10.1093/nar/gkp355. (http://biodb.jp/)

2. How to create hyperlinks using the system

(1) A simple method

In order to create hyperlinks using the CGI-program of the Hyperlink Management System, use the following URL as a target URL..
			http://biodb.jp/hfs.cgi?id=[ID]&type=[ID Type]&db=[Database Name]
		
The parameters given to the CGI-program are as follows.

  1. [ID]
    Source ID (original ID).

  2. [ID Type]
    The type of source ID. Choose from below.
    ID list

  3. [Database name]
    The name of target database. Choose from below.
    Database list

Sample
The hyperlink to the "Transcript view" of H-InvDB using the INSD accession number "BC053657" will be the following URL.
		http://biodb.jp/hfs.cgi?id=BC053657&type=ACC_ID&db=TRANSCRIPTVIEW
		

In HTML, you can write as follows.
		<a href='http://biodb.jp/hfs.cgi?id=BC053657&type=ACC_ID&db=TRANSCRIPTVIEW'>BC053657</a>
		Sample:BC053657
		

ID list for human
No.FormatOutline
1ACC_IDAccession Number
2HIT_IDH-Inv transcript ID (HIT)
3HIX_IDH-Inv cluster ID (HIX)
4HIP_IDH-Inv protein ID (HIP)
5UNIPROT_IDUniProt Accession Number
6GENE_SYMBOLHUGO gene symbol
7REF_SEQRefSeq
8OMIM_IDOMIM ID
9GENE_IDGeneID
10PUBMED_IDPubMed ID
11JSNP_IDdbSNP rs#
12MS_IDMarker Name
13PDB_IDPDB ID
14FR_IDfRNAdb ID
15ENST_IDEnsembl Transcript ID
16ENSG_IDEnsembl Gene ID
17CLONE_IDClone ID (by NBRC)
18FLJ_IDFLJ ID (by NBRC)
19HPRD_IDHPRD ID
20CIPRO_IDCIPRO ID



ID list for mouse
No.FormatOutline
1MMU_MGI_IDMGI ID
2MMU_ACC_IDAccession Number
3HIT_IDH-Inv transcript ID (HIT)
4MMU_UNIPROT_IDUniProt Accession Number
5MMU_REF_SEQRefSeq
6MMU_GENE_IDGeneID
7MMU_PUBMED_IDPubMed ID
8MMU_ENST_IDEnsembl Transcript ID
9MMU_ENSG_IDEnsembl Gene ID
10MMU_CLONE_IDClone ID(FANTOM)



Database list for human
No.FormatOutline
1TRANSCRIPTVIEWH-InvDB (Transcript view)
2LOCUSVIEWH-InvDB (Locus view)
3GINTEGRAH-InvDB (G-integra)
4PPIH-InvDB (PPI view)
5NUCLEOTIDENCBI (Nucleotide)
6GENBANKNCBI (GenBank)
7ENTREZGENENCBI (Entrez Gene)
8OMIMNCBI (OMIM)
9PUBMEDNCBI (PubMed)
10GEMDBJGeMDBJ
11HUGOHUGO
12MUTATIONVIEWMutationView
13HGOLDH-GOLD
14PDBPDB
15UNIPROTUniProt
16ENSTEnsembl Transcriptview
17ENSGEnsembl Geneview
18GGDBGGDB
19FRNADBfRNAdb
20NBRCNBRC
21HGPDHGPD
22KEGGKEGG Gene
23PATHWAYKEGG Pathway
24HPRDHPRD
25LEGENDALEGENDA
26EVOLAEVOLA
27HDBASH-DBAS
28GCOMPASSG-Compass
29PROTEINVIEWProtein View
30CIPROCIPRO
31HANGELH-ANGEL
32FLJHFLJ Human cDNA
33VARYSYSDBVarySysDB



Database list for mouse
No.FormatOutline
1NUCLEOTIDENCBI (Nucleotide)
2GENBANKNCBI (GenBank)
3ENTREZGENENCBI (Entrez Gene)
4PUBMEDNCBI (PubMed)
5UNIPROTUniProt
6ENSTEnsembl Transcriptview
7ENSGEnsembl Geneview
8KEGGKEGG Gene
9PATHWAYKEGG Pathway
10EVOLAEVOLA
11MGIMGI
12IKMCIKMC
13FANTOMFANTOM

(2) Using Real-Time Link Generator

By a web-service connection to the Real-Time Link Generator of Hyperlink Forwarding System, you can show hyperlinks only when data exists at the destination. This is useful because users can know whether the link is active or not. If there is no data at the destination, "No Link" will be shown. Please see the HTML sources of the following two examples, and copy and paste them as you like (you need to change only IDs).
Sample 1
Sample 2
The sample 1 shows hyperlinks to Locus view of H-InvDB based on a OMIM ID. The sample 2 shows hyperlinks to 24 kinds of databases. By simply inserting several lines of JavaScript in your HTML, you can use this function.

3. All database search

By specifying IDs of any kind, this system searches for IDs in other databases that correspond to the specified IDs. By default, [All Databases] is selected as a database to open.

Usage


    Search page

    (1)The form of converted ID is selected.
    ID/Type list

    (2)Input converted ID.

    (3)The data base of the forwarding destination is selected.
    Database list

    (4)Please click "Search".
    The search result will be displayed.


    Result page

4. ID converter system

ID converter system

5. Downloading ID tables

You can download corresponding tables of two IDs. Select two IDs, push the search button, and start downloading the file of corresponding tables. The files are in tab-delimited text format.

6. Web Service

Web service

7. Collected databases/IDs

This system acquires data from the following data bases.
We analyze correspondence of data IDs based on the following ID networks. By tracing the paths connected by solid lines, we make corresponding tables for all possible pairs of IDs.
database for for human

H-InvDB   http://www.h-invitational.jp/hinv/ahg-db/index.jsp

-Accession Number
-H-Inv transcript ID(HIT)
-H-Inv cluster ID (HIX)
-H-Inv protein ID (HIP)

NCBI   http://www.ncbi.nlm.nih.gov/

-Accession Number
-HUGO gene symbol
-RefSeq
-OMIM ID
-GeneID
-PubMed ID

HUGO   http://www.genenames.org/

-HUGO gene symbol
-RefSeq

H-GOLD   http://www.h-invitational.jp/gdbs/

-Accession Number
-H-GOLD Marker ID

GeMDBJ   https://gemdbj.nibio.go.jp/

-HUGO gene symbol
-dbSNP rs#

PDBj   http://www.pdbj.org/

-UniProt Accession Number
-PDB ID

MutationView   http://mutview.dmb.med.keio.ac.jp/MutationView/jsp/mutview/index.jsp

-HUGO gene symbol
-OMIM ID

Ensembl   http://www.ensembl.org/index.html

-HUGO gene symbol
-Ensembl Transcript ID (ENST)
-Ensembl Gene ID (ENSG)

UniProt   http://www.uniprot.org/

-UniProt Accession Number
-Accession Number

fRNAdb   http://www.ncrna.org/frnadb

-Accession Number
-fRNAdb ID

GGDB   http://riodb.ibase.aist.go.jp/rcmg/ggdb/

-HUGO Gene Symbol
-RefSeq

HGPD   http://www.HGPD.jp/

-Accession Number
-Clone ID
-FLJ ID

KEGG   http://www.genome.jp/kegg/

-GeneID
-KEGG Gene ID
-KEGG Pathway ID

HPRD   http://www.hprd.org/

-GeneID
-HPRD ID

NBRC   http://www.nbrc.nite.go.jp/e/index.html

-Accession Number
-Clone ID
-FLJ ID

LEGENA   http://h-invitational.jp/legenda/top.htm

-GeneID

Evola   http://www.h-invitational.jp/evola/search.html

-Mouse Accession Number
-H-Inv transcript ID(HIT)

H-DBAS   http://h-invitational.jp/h-dbas/

-Accession Number
-H-Inv cluster ID (HIX)

G-Compass   http://h-invitational.jp/g-compass/

-Accession Number
-H-Inv transcript ID(HIT)

Protein View   http://h-invitational.jp/hinv/help/help_index.html

-Accession Number
-H-Inv protein ID (HIP)

CIPRO   http://cipro.ibio.jp/

-Accession Number
-CIPRO ID

H-ANGEL   http://h-invitational.jp/hinv/h-angel/

-Accession Number
-H-Inv protein ID (HIP)

FLJ Human cDNA   http://flj.hinv.jp/

-Accession Number
-Clone ID
-FLJ ID

VarySysDB   http://h-invitational.jp/varygene/home.htm

-Accession Number
-H-Inv transcript ID(HIT)


Figure. ID network for human molecular data


database for mouse

NCBI   http://www.ncbi.nlm.nih.gov/

-Accession Number
-HUGO gene symbol
-RefSeq
-GeneID
-PubMed ID

Ensembl   http://www.ensembl.org/index.html

-HUGO gene symbol
-Ensembl Transcript ID (ENST)
-Ensembl Gene ID (ENSG)

UniProt   http://www.uniprot.org/

-UniProt Accession Number
-Accession Number

KEGG   http://www.genome.jp/kegg/

-GeneID
-KEGG Gene ID
-KEGG Pathway ID

Evola   http://www.h-invitational.jp/evola/search.html

-H-Inv transcript ID(HIT)
-Mouse Accession Number

MGI   http://www.informatics.jax.org/

-MGI ID
-Mouse Accession Number

IKMC   http://www.knockoutmouse.org

-MGI ID

FANTOM   http://fantom3.gsc.riken.jp/

-Mouse Accession Number
-Clone ID(FANTOM)




Figure. ID network for mouse molecular data

8. Release history

  • December 26, 2007 Official public release of Hyperlink Management System.
  • June 19, 2008 PDBj, MutationView were included. Official public release of ID Converter System.
  • January 06, 2009 Ensembl, GGDB and HPRD were included.
  • January 12, 2009 This system was licensed under a Creative Commons License.
  • August 20, 2009 "All Databases" was added as a target database of Hyperlink Management System.
  • September 29, 2009 KEGG were included.
  • October 21, 2009 HPRD were included.
  • December 28, 2009 "previous symbols" of HUGO Gene Symbol were added.
  • January 28, 2010 PubMed, GenBank, OMIM and NBRC were included.
  • February 25, 2010 Downloading data ID tables was enabled. LEGENDA and Evola were included.
  • April 08, 2010 For mouse,NCBI,Ensembl,Uniprot,KEGG,Evola,MGI and IKMC were added.
  • April 20, 2010 FANTOM were included.
  • May 26, 2010 H-DBAS, G-Compass, Protein View were included.
  • Jun 30, 2010 CIPRO, H-ANGEL, FLJ Human cDNA, VarySysDB were included.